Dr Murphy Wan
Biography
Dr. Wan completed her PhD at the University of Hong Kong before joining Lund University, Sweden, as a Postdoctoral Fellow, where she investigated the transcriptional regulation of disease severity in bacterial kidney infections.
She is currently a Senior Lecturer in Biomedical Sciences at the 乱伦社区. Since establishing her research lab in 2021, her work has focused on developing novel therapeutics for cancer and neurodegenerative diseases, leveraging cutting-edge precision medicine approaches. Her lab integrates multi-omics technologies鈥攊ncluding genomics, transcriptomics, proteomics, and metabolomics鈥攖o uncover the molecular mechanisms underlying complex diseases.
Dr. Wan has published in high-impact journals, including Nature Biotechnology, Nature Communications, ACS Pharmacology & Translational Science, Critical Reviews in Food Science and Nutrition, and Scientific Reports. She is frequently invited to review manuscripts for leading journals and present her research at international conferences. Additionally, she serves as an active member and Network Coordinator of the ARUK South Coast Network.
Research interests
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Natural Compounds in Cancer Therapy 鈥 Investigating the therapeutic potential of bioactive molecules in colorectal cancer, supported by funding from the Academy of Finland.
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Targeting Cancer Signaling Pathways 鈥 Identifying and developing novel small-molecule compounds through computational biology, advanced bioinformatics, and cancer cell biology.
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Neuroinflammation and Alzheimer鈥檚 Disease 鈥 Exploring the role of bacterial infections and systemic inflammation in Alzheimer鈥檚 disease. Supported by the ARUK South Coast pump-priming grant, this research investigates amyloid-beta in the gut-brain-microbiota axis, examining how bacterial infection and inflammation contribute to disease development and identifying novel therapeutic targets.
More information can be found at https://www.mwanlab.com/
Dr Murphy Wan welcomes MRes and PhD students. Please email murphy.wan@port.ac.uk to discuss further.
Research outputs
2025
Ehambarampillai, D., Wan, M. L. Y.
9 Apr 2025, In: Chinese Medicine. 20, 1, 34p., 47
Research output: Article
Belelli, D., Lambert, J. J., Wan, M., Monteiro, R., Nutt, D. J., Swinny, J.
11 Mar 2025, In: Brain
Research output: Article
Wan, M., Co, V. A., Turner, P. C., Shah, N. P., El-Nezami, H.
20 Feb 2025, In: Journal of Food Science. 90, 2, 17p., e70079
Research output: Article
Lee, P., Co, V. A., Yang, Y., Wan, M. L. Y., El-Nezami, H., Zhao, D.
1 Jan 2025, In: Food Chemistry. 463, 9p., 141371
Research output: Article
2024
Co, V. A., El-Nezami, H., Liu, Y., Twum, B., Dey, P., Cox, P. A., Joseph, S., Agbodjan-Dossou, R., Sabzichi, M., Draheim, R., Wan, M. L. Y.
8 Mar 2024, In: ACS Pharmacology & Translational Science. 7, 3, p. 863-877
Research output: Article
Tran, T. H., Wan, M., Ambite, I., Cavalera, M., Grossi, M., H谩膷ek, J., Esmaeili, P., Carneiro, A. N. B. M., Chaudhuri, A., Ahmadi, S., Svanborg, C.
15 Feb 2024, In: Scientific Reports. 14, 21p., 3838
Research output: Article
2023
Ambite, I., Tran, T. H., Butler, D., Cavalera, M., Wan, M., Ahmadi, S., Svanborg, C.
31 Dec 2023, In: Pathogens. 13, 1, 18p., 42
Research output: Article
Hien, T. T., Ambite, I., Wan, M., Cavalera, M., Esmaeili, P., Chaudhuri, A., Sabari, S., Babjuk, M., Svanborg, C.
1 Aug 2023, In: International Journal of Cancer. 153, 3, p. 584-599
Research output: Article
Chavoshi, H., Taheri, M., Wan, M. L. Y., Sabzichi, M.
1 Jul 2023, In: Process Biochemistry. 130, 9p.
Research output: Article
2022
Butler, D. S. C., Ambite, I., Wan, M., Tran, T. H., Wullt, B., Svanborg, C.
1 Jul 2022, In: Nature Reviews Urology. 19
Research output: Article